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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
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Pregnancy and Breastfeeding

Do not take Cialis if you are pregnant or plan to become pregnant. If you think you are having a medical emergency, call your doctor or emergency services immediately.

If you become pregnant while taking Cialis, consult your doctor before taking the medication.

Do not use Cialis if you breastfeeding, as it could pass into into human milk and cause harm to the infant.

Do not discontinue taking Cialis if you reach pregnancy and have a serious medical condition, such as low blood pressure, irregular heartbeat, or fainting. If you have any complications such as severe dizziness, low blood pressure, or a rash, contact your doctor immediately.

Do not use Cialis if you are currently receiving treatment for a medical condition such as a urinary tract infection, cisplasia, uterinitis, or prostatitis.

Before you begin taking Tadalafil generic, its important to carefully read the Patient Information Leaflet. Make sure to review it each time you get a refill.

Take Tadalafil dosage orally, either with or without food, as directed by your healthcare provider. Tadalafil dosage should not exceed more than once a day. Swallow the tablet whole. Do not split it or crush unless advised.

Your daily dosage will depend on your medical condition, how you respond to medications, and any other medications you currently take. Before you take ED treatment pills, ensure that you inform your healthcare service provider of any prescription drugs, over-the-counter medicines, and any other supplements you take.

If you are also using finasteride alongside Tadalafil to treat any symptoms of benign prostatic hyperplasia (BPH), discuss the duration of treatment and dosage you will need with your healthcare provider.

For erectile dysfunction (ED), tadalafil citrate may be prescribed in two ways:

  • You may take it as needed, usually at least 30 minutes before sexual activity, with its effects potentially lasting up to 36 hours.
  • Your doctor may recommend taking generic Cialis regularly, once a day.

Follow your doctors instructions carefully based on your specific needs and condition.

If you are using tadalafil citrate medication for ED dysfunction and BPH, take it daily as directed by your doctor. To ensure you do not forget, take it at the same time each day.

Keep your healthcare practitioner informed if your medical condition does not improve or worsens during treatment.

irlwinds:iganismcommentaryTadalafil generic
  • Take this medication orally; however, your doctor may recommend taking it daily to maximize benefits.
  • If you have any side effects, discuss with your doctor how soon you should monitor side effects with your healthcare provider.
  • Follow your doctor's instructions regarding dosage and time of day you take tadalafil generic.
  • LearnMoreHelp|Help For Side Effects
    • If you are experiencing erectile dysfunction (ED), tadalafil generic may be prescribed in two ways:
      • You may take it regularly, usually at least 30 minutes before sexual activity, with or without prior to taking tadalafil generic.
      • Your doctor may recommend tadalafil generic for another reason.

    Ask your healthcare provider about any side effect you may experience if you:

    • Have or ever had allergic reactions to tadalafil or any other medications.
    • Have a history of liver disease, high blood pressure, high cholesterol, or diabetes.
    • Have kidney disease or abnormal liver tests.
    • Are taking other medications that may affect the rate at which tadalafil generic absorption occurs.
    • Are a fan of nitrates (used for chest pain or angina), used for angina
    • Take riociguat (a medication that works by increasing urine production) as needed, but it does not work as well as nitrates
    • Take ritonavir (an HIV protease inhibitor) as needed, but it does not work well as well as nitrates
    • Take rifampin (a medication used to treat bacterial infections) used for heart, blood, and kidney disorders
    • Take cobicistat (a medicine to treat arthritis) as needed, but it does not work well as well as cilostazol (an anti-arrhythmic)
    • Take ritonavir (an HIV protease inhibitor) used for heart, blood, and kidney disorders
    • Take azole antifungals (used to treat HIV infection).

    This is not a complete list of potential side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

    Learn More About Tadalafil Generic

    What is Tadalafil generic used for?

    Tadalafil generic belongs to the group of phosphodiesterase type 5 inhibitors (PDE5 inhibitors). It works by helping blood vessels in your penis, causing it to expand and blood to pump blood into the penis. Blood flow to the penis can increase, decrease, or intensify muscle spasms ( seizures) caused by other medications you are taking.

    Tadalafil 20mg Tabletsare a prescription medication used in the treatment of erectile dysfunction (ED) in men. They belong to a class of medications called phosphodiesterase type 5 (PDE5) inhibitors and work by helping to relax the blood vessels in the penis, allowing for increased blood flow and resulting in an erection.

    1. You should consider taking this medication exactly as prescribed by your doctor. This includes medical history, physical and psychological well-being, your sexual partner(s) and/or the effects of other medications. This medication should be taken regularly on a daily basis to any sexual activity in order to achieve the best results.

    2. You should follow your doctor’s instructions about the duration of the treatment. Usually, the effects of this medication will last between 36 hours and 4 hours. However, it is important to note that the duration may vary depending on factors such as the individual’s age, overall health, and the severity of ED. Therefore, it is crucial to take this medication as directed by your doctor.

    Important Considerations: This medication is generally well-tolerated. However, in some cases, it may lead to side effects such as headache, nausea, dizziness, and stomach upset. Always follow your doctor’s instructions and consult them if you have any concerns.

    Dosage and Administration

    The dosage of this medication may vary depending on the individual’s specific needs and the medication’s effectiveness. Typically, the duration of treatment is 20 to 30 minutes. However, it is important to note that this medication should only be taken when prescribed by a doctor, as there may be side effects associated with it.

    Side Effects

    Some individuals may experience side effects such as headache, facial flushing, indigestion, and nasal congestion. In rare cases, some side effects may be more severe and require immediate medical attention. It is important to tell your doctor about all your current medications, supplements, and herbal products before starting this medication as they can help determine if it is safe for you to take it.

    Drug Interactions

    This medication can interact with other medications and supplements. Therefore, it is important to talk with your doctor before taking this medication. Be aware that certain medications and supplements can interact with tadalafil, increasing the risk of side effects. Therefore, avoid taking this medication while taking tadalafil as it may increase the risk of side effects.

    This medication should not be taken with nitrates, as this combination may result in a dangerous drop in blood pressure. In case you experience dizziness or lightheadedness while taking this medication, contact your doctor immediately. Inform your doctor if you have any medical conditions, especially if any of the following apply to you: allergies to medicines, foods, or other substances; heart problems; liver or kidney disease; or other medications you are taking.

    Other Important Information

    This medication is not intended for use by men. This medication should not be taken by women or children. If you are having trouble taking the medication, you should talk to your doctor.

    Approved By: The Food and Drug Administration (FDA) has approved this medication for medical use only. It is not intended for use by women or children.

    Warning: This medication may cause dizziness or lightheadedness, and should be avoided in those cases. If you experience sudden vision or hearing loss while taking this medication contact your doctor immediately.

    Storage: Store at room temperature, between 68 and 77 degrees F (20 and 25 degrees C).

    ApprovedBy: The Food and Drug Administration (FDA) has approved this medication for medical use only.ApprovedBy: The FDA has approved this medication for medical use only.

    Whether you can take Tadalafil at the same time as your other medications will depend on which medications you are taking.

    You are required to complete a short medical consultation questionnaire that asks for any medications that you are prescribed from your GP and will indicate the medications that can’t be taken alongside Tadalafil.

    There are several medicines which should not be taken concurrently with Tadalafil. Medicines which can have potentially serious interactions with Tadalafil include :-

    • Any alpha-blocker medicines e.g. doxazosin (Cardura), alfuzosin (Xatral), tamsulosin, terazosin, or Flomax, that you can buy in the pharmacy. (These medicines may be used to treat prostate problems or high blood pressure).

    • Isosorbide mononitrate, isosorbide dinitrate, or use a GTN spray or tablets

    for chest pain or use Rectogesic ointment?

    • Nicorandil (Ikorel), used to treat angina

    • Cimetidine, used to treat stomach or duodenal (peptic) ulcers

    • Theophylline, used to treat asthma

    • Antibiotics:- Clarithromycin, Erythromycin and Telithromycin

    • Anti-fungals such as itraconazole and ketoconazole

    • Seizure medication:- carbamazepine, oxcarbazepine, phenobarbital, phenytoin and primidone

    • Heart or blood pressure medication:- disopyramide, amiodarone, quinidine and procainamide

    • Anti-viral medication:- telaprevir, atazanavir, retonavir, indinavir, saquinavir and cobicistat

    • Recreational drugs:- amyl nitrate (poppers)

    If you are taking any prescribed medication from your GP then you can simply write those in the “Is there any other medical information that you think our doctor should know?” section on the medical questionnaire. Then, our doctor will know whether the Tadalafil is safe for you to take.

    Read available consultation questionnaire information online for “Tadalafil at the same time as other medications.”

    To orderTadalafil at the same time as my other medications, as well as any time you need advice or to order the medical questionnaire work with “Tadalafil at the same time as my other medications,” you will be given a (GPS) and aacles that will prompt you to proceed. The O’McCubie®a combination is safe for you to use. You can take it with or without food. However, it is important to be able to take it at the same time as your other medications to be safe.

    Summarised clinical information for “Tadalafil at the same time as my other medications.