1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).
2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.
3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.
Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:
The presence of apill in a grapefruit smoothie can affect blood pressure in sensitive individuals. If you have a infections that require aGrapefruit and Grapefruit smoothie, discuss with your doctor about how the medication can be taken with the help of the pill.
A lower risk of infections with Grapefruit and Grapefruit smoothie beverages: While Grapefruit and Grapefruit smoothies usually have a lower daily dosage than their grapefruit juice counterparts, there are some infections that require aGrapefruit and Grape smoothiethat do not require a lower dosage.
Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness.
General Product Description
Cialis (tadalafil) is a popular medication used to treat erectile dysfunction (ED) and enlarged prostate in men. It works by increasing blood flow to the penis, helping to achieve and maintain an erection. Cialis is manufactured by GlaxoSmithKline and comes in various strengths and formulations. It is important to note that Cialis should only be used under the guidance of a healthcare professional, as it may not be suitable for everyone. It is also important to consult with your doctor before use if you have any underlying medical conditions, such as high blood pressure, liver or kidney disease, heart failure, or diabetes.
Key Features of Cialis:
How Cialis Works:
Cialis belongs to a class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors. It works by helping to relax the blood vessels in the penis, thereby increasing blood flow, which helps to achieve and maintain an erection.
Cialis is not intended for women or children. Its safety and effectiveness have not been established. Cialis should not be used by men who are or may become pregnant, as it can harm the male fetus.
Directions for Use:
Take Cialis by mouth as directed by your doctor, approximately 30 minutes before sexual activity. The dose may be based on your medical condition and response to treatment. Cialis may be taken with or without food, but it is recommended to take it at the same time each day. Do not take Cialis more than once a day. Swallow the pill whole with a glass of water.
Precautions and Warnings:
Please consult your doctor or pharmacist if you have any other medical conditions or medications, so that appropriate treatment can be provided.
Product Code :
CALCIUM DISPENSED DYE: ACID: ACID: ACNAPINEHN
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Cialis (Tadalafil) Tablets Price In Pakistanis a popular erectile dysfunction treatment that is used to treat erectile dysfunction (ED). Cialis is a PDE5 inhibitor which increases blood flow to the penis by relaxing the muscles in this section. This section allows men to get an erection and have sex. You can also use this drug to treat ED by relaxing the muscles in the blood vessels that supply blood to the penis. Cialis Tablets are used to treat ED in men who have impotence or a hard time with impotence or have low testosterone levels. Cialis can treat erectile dysfunction and treat or prevent erectile dysfunction in men. It may also be used to treat the following problems in men: - Erectile Dysfunction - Dysfunction related to low blood flow - Low testosterone levels in men - Hormone replacement therapy - Erectile dysfunction - Reduced blood flow to the penis - Pulmonary hypertension or high blood pressure - High blood pressure or abnormal blood pressure in the lungs - Acute coronary syndrome - Men who have a history of blood clots in the lungs - Pulmonary hypertension - High blood pressure in the lungs - Anemia or an abnormality in blood redness / weakness - Acute leukemia - Men who are taking men with a family history of heart disease or strokes - High blood pressure in men's circulatory system
Tadalafil (Cialis) is used to treat erectile dysfunction in menCialis works by relaxing the muscles in the blood vessels that supply blood to the penis, thereby increasing blood flow. This increases the ability to get an erection.
Cialis is available in different dosages and is available in the following forms:
Cialis is available in the following strengths:
Tablets
5mg and 10mg tablets
Most side effects of Cialis are temporary and go away once the medication is stopped. However, if you experience side effects such as headaches, facial flushing, indigestion, nasal congestion or indigestion with a nasal discharge, you should see your doctor immediately. If you are experiencing the following symptoms, speak to your doctor immediately.
Do not use Cialis if:
Get emergency help if you have signs of an allergic reaction to Cialis:
Do not use Cialis if you are taking any nitrate medications for chest pain, heart problems or blood pressure problems. Cialis can cause a sudden decrease in blood pressure which may cause dizziness, fainting, heart attack or stroke.
The aim of the study was to assess the effectiveness and safety of tadalafil (Cialis) in the treatment of patients with pulmonary arterial hypertension (PAH), a condition in which the left ventricle is unable to pump blood to the lungs. We aimed to compare the drug effect between the two treatment groups.
Patients
Eligible patients were those who had:
Study design
We conducted a cross-sectional study. Patients were randomised to one of two treatment groups: tadalafil (Cialis) 30 or 60 mg (1 mg) daily with no treatment in the evening; or sildenafil (Viagra) 40 or 80 mg (1 mg) daily with no treatment in the evening. In the treatment group, tadalafil (Cialis) 30 mg (1 mg) daily, compared with sildenafil (Viagra) 40 mg (1 mg), were administered for the treatment of PAH.
Data collection
Patients were interviewed to collect information on the patient's history, physical and psychological symptoms and quality of life. Efficacy assessments included the International Index of Erectile Function (IIEF) scale, the Pulmonary Function Impairment Questionnaire (PRQ-24) and the Global Assessment Question (GAB).
Statistical analysis
SPSS version 16.0 (SPSS, Chicago, IL, USA) was used for the analysis. A two-factor structure was considered. Patients' answers to the questions on IIEF, GAB and PRQ-24 were entered into a two-factor analysis. The ANOVA was used to test the effect of tadalafil (Cialis) 30 mg (1 mg) daily with no treatment on global assessment symptoms, functional capacity and global outcome measures. The Chi-square test was used to compare the two treatment groups. The results of the ANOVA analysis were compared using an analysis of variance (ANOVA) with the level of statistical significance (α<0.05).
The mean difference (MD) in the IIEF, GAB and PRQ-24 scores was 2.8 (SD 1.3) and 2.7 (SD 1.6) points, respectively. There were no significant differences between the treatment groups in the PRQ-24 scores. There was a significant difference in GAB scores between the two treatment groups (p<0.05).
The mean difference in the PRQ-24 scores was -0.19 (SD 1.3) and -0.25 (SD 1.5) points for Cialis and sildenafil, respectively (p<0.05).
The mean difference in GAB scores between the two treatment groups was -0.24 (SD 1.6) and -0.33 (SD 1.7) points, respectively (p<0.05).
Conclusion
The study showed that tadalafil 30 mg (1 mg) daily with no treatment could be a safe treatment for patients with PAH. It is recommended to continue tadalafil therapy for at least 12 months in patients with PAH. The effect of the treatment was statistically significant in patients with PAH and in patients with other systemic conditions.
Keywords
PAH, pulmonary arterial hypertension
Sildenafil, erectile dysfunction
Source
This study was funded by the Swedish Research Council (S sclerosis); the Swedish National Agency for Education and Research on Health and the Swedish Research Council (Sfena).
© Copyright 2019 Physicians Postgraduate Press, Inc. All rights reserved. This is an Open Access article, which contains all the information and data that you need to know about the research and its outcomes.https://www.preclinicaltrials.
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